I'm giving Restic a go for backups with a NixOS system. The integration on NixOS is pretty easy to set up and backing up to Minio was painless. I still need to work on the sequencing from services that won't work with just a disk copy (sqlite mostly I think).

I've mostly seen people ask about Borg in the self-hosting community, but I wanted something S3-compatible natively and Borg doesn't seem to fit that.